Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182657 | 0.89 | EGFR (0.49) | EGFRNR4A1NR4A2NR4A3PLA2G4B | |
| SCHEMBL9185432 | 0.85 | L3MBTL1 (0.45) | NR4A2ALDH1A1MAPTL3MBTL1ALOX5 | |
| SCHEMBL9182611 | 0.78 | L3MBTL1 (0.50) | MAPTRAB9AL3MBTL1LMNAHDAC6 | |
| SCHEMBL8062854 | 0.77 | FFAR1 (0.54) | ALOX5FFAR1FFAR4 | |
| SCHEMBL9185267 | 0.77 | L3MBTL1 (0.53) | MAPTRAB9AL3MBTL1LMNAHDAC6 | |
| SCHEMBL8072697 | 0.76 | ALOX5 (0.47) | NR4A1NR4A2NR4A3PLA2G4BMAOB | |
| SCHEMBL9186283 | 0.72 | MAPT (0.49) | MAOBALDH1A1MAPTHTTRAB9A | |
| SCHEMBL1557011 | 0.71 | FFAR1 (0.71) | EGFRNR4A1NR4A2NR4A3PLA2G4B | |
| SCHEMBL958582 | 0.71 | EGFR (0.69) | EGFRNR4A1NR4A2NR4A3PLA2G4B | |
| SCHEMBL6811506 | 0.71 | EGFR (0.69) | EGFRNR4A1NR4A2NR4A3PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664780-A1 | 10-SUBSTITUTED 1,8-DIHYDROXY-9(10H) ANTHRACENONE PHARMACEUTICALS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-08-02 | — | — | EP | disclosed |