Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185432 | 0.85 | L3MBTL1 (0.45) | MAPTALDH1A1L3MBTL1ALOX15KDM4E | |
| SCHEMBL9182657 | 0.84 | EGFR (0.49) | MAPTALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL9178368 | 0.84 | ALDH1A1 (0.52) | MAPTALDH1A1L3MBTL1KMT2ANPC1 | |
| SCHEMBL9182611 | 0.83 | L3MBTL1 (0.50) | MAPTL3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL9185267 | 0.82 | L3MBTL1 (0.53) | MAPTL3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL8073615 | 0.73 | ELANE (0.42) | MAPTALDH1A1HPGDALOX15SMN1; SMN2 | |
| SCHEMBL9186247 | 0.72 | EGFR (0.53) | MAPTALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL8064520 | 0.72 | ALDH1A1 (0.39) | MAPTALDH1A1L3MBTL1HPGDALOX15 | |
| SCHEMBL28184058 | 0.71 | ALDH1A1 (0.50) | MAPTALDH1A1L3MBTL1HPGDALOX15 | |
| SCHEMBL14113261 | 0.70 | MAOA (0.56) | MAPTALDH1A1L3MBTL1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664780-A1 | 10-SUBSTITUTED 1,8-DIHYDROXY-9(10H) ANTHRACENONE PHARMACEUTICALS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-08-02 | — | — | EP | disclosed |