Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186536 | 1.00 | PTGES (0.43) | PTGESALOX5GPR119THRATHRB | |
| SCHEMBL9187161 | 0.99 | THRA (0.43) | PTGESALOX5GPR119THRATHRB | |
| SCHEMBL9185574 | 0.99 | THRA (0.43) | PTGESALOX5GPR119THRATHRB | |
| SCHEMBL9185564 | 0.99 | THRA (0.43) | PTGESALOX5GPR119THRATHRB | |
| SCHEMBL9187164 | 0.99 | THRA (0.43) | PTGESALOX5GPR119THRATHRB | |
| SCHEMBL9188863 | 0.88 | TDP1 (0.44) | PTGESALOX5GPR119CNR2ITGB3 | |
| SCHEMBL9188856 | 0.88 | TDP1 (0.44) | PTGESALOX5GPR119CNR2ITGB3 | |
| SCHEMBL9184508 | 0.88 | GPR119 (0.39) | PTGESALOX5GPR119CNR2ITGB3 | |
| SCHEMBL9345318 | 0.86 | TDP1 (0.43) | GPR119CNR2ITGB3ITGA2BCNR1 | |
| SCHEMBL9590846 | 0.86 | TDP1 (0.43) | GPR119CNR2ITGB3ITGA2BCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423520-B1 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GMBH (DE) | 1995-08-02 | — | — | EP | disclosed |