Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.57 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9412462 | 0.99 | ITGB3 (0.56) | ITGB3ITGA2BITGA2POLBGAA | |
| SCHEMBL9412623 | 0.91 | MAPT (0.46) | ITGB3ITGA2BITGA2POLBGAA | |
| SCHEMBL9412439 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BITGA2 | |
| SCHEMBL9412511 | 0.88 | MAPT (0.45) | ITGB3ITGA2BITGA2POLBGAA | |
| Bromide SCHEMBL9412639 | 0.87 | ITGB3 (0.51) | ITGB3ITGA2BITGA2MAPT | |
| SCHEMBL9412612 | 0.86 | ITGB3 (0.42) | ITGB3ITGA2BITGA2POLBGAA | |
| SCHEMBL9412727 | 0.86 | POLB (0.46) | ITGB3ITGA2BITGA2POLBGAA | |
| SCHEMBL9412665 | 0.86 | MAPT (0.45) | ITGB3ITGA2BITGA2POLBGAA | |
| SCHEMBL9412452 | 0.85 | MAPT (0.44) | ITGB3ITGA2BITGA2POLBGAA | |
| SCHEMBL9412444 | 0.85 | HDAC6 (0.45) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | claimed |
| JP-7002839-A | — | — | None | — | — | JP | disclosed |
| JP-H072839-A | CONDENSED FIVE-MEMBERED HETEROCYCLIC COMPOUND, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT | DR KARL THOMAE GMBH | 1995-01-06 | — | — | JP | disclosed |
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |