Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.56 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | IDH1 | O75874 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412586 | 0.90 | RORC (0.46) | ITGB3ITGA2BITGA2HDAC6HDAC1 | |
| SCHEMBL9188544 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BITGA2 | |
| Bromide SCHEMBL9412462 | 0.87 | ITGB3 (0.56) | ITGB3ITGA2BITGA2 | |
| SCHEMBL9412548 | 0.86 | HPGD (0.45) | ITGB3ITGA2BHDAC6HDAC1RORC | |
| Bromide SCHEMBL9412639 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BITGA2HDAC1 | |
| Bromide SCHEMBL9412577 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BITGA2HDAC1 | |
| Bromide SCHEMBL9412436 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2BITGA2HDAC1 | |
| SCHEMBL9412623 | 0.79 | MAPT (0.46) | ITGB3ITGA2BITGA2HDAC6IDH1 | |
| Bromide SCHEMBL9412576 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BITGA2HDAC1 | |
| SCHEMBL9412611 | 0.79 | MAPT (0.51) | ITGB3ITGA2BITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |