Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329417 | 0.82 | CYP1A2 (0.52) | CYP1A2ALDH1A1ALOX15TSHR | |
| SCHEMBL8795 | 0.82 | CYP1A2 (0.52) | CYP1A2ALDH1A1ALOX15TSHR | |
| SCHEMBL11779604 | 0.76 | GAA (0.30) | — | |
| SCHEMBL1965758 | 0.73 | CYP1A2 (0.45) | CYP1A2ALDH1A1ALOX15TSHR | |
| SCHEMBL479536 | 0.73 | — | — | |
| SCHEMBL2633403 | 0.71 | CYP1A2 (0.44) | CYP1A2ALDH1A1ALOX15TSHR | |
| SCHEMBL9529398 | 0.71 | CYP1A2 (0.44) | CYP1A2ALDH1A1ALOX15TSHR | |
| SCHEMBL10351075 | 0.71 | — | — | |
| SCHEMBL1577050 | 0.71 | HSP90AA1 (0.50) | CYP1A2ALDH1A1ALOX15TSHR | |
| SCHEMBL7250707 | 0.71 | TP53 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933785-A | Azo compounds | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | claimed |
| EP-0380019-B1 | Methadone fluorescence polarization immunoassay | ABBOTT LAB (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5336622-A | Competitive binding using a fluorescent dye tracer; monitoring dosage in biological fluid; sensitivity; accuracy; efficiency | ABBOTT LABORATORIES (US) | 1994-08-09 | — | — | US | disclosed |
| US-5258512-A | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0380019-A2 | Methadone fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4939264-A | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1990-07-03 | — | — | US | disclosed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3933785-A | Azo compounds | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |