Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195413 | 0.84 | FFAR1 (0.54) | FFAR1 | |
| SCHEMBL9195927 | 0.80 | ACACB (0.49) | FFAR1ACACB | |
| SCHEMBL9299537 | 0.76 | ALOX5 (0.45) | FFAR1 | |
| SCHEMBL9192595 | 0.75 | ACACB (0.42) | FFAR1PTGESACACB | |
| SCHEMBL9192422 | 0.75 | FFAR1 (0.58) | FFAR1PTGESAKR1C3GRM5CHRNB2 | |
| SCHEMBL9195264 | 0.74 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL9192424 | 0.73 | ALOX5 (0.48) | FFAR1 | |
| SCHEMBL13907278 | 0.72 | CYP2A6 (0.62) | FFAR1GRM5CHRNB2CHRNA4 | |
| SCHEMBL9195929 | 0.72 | ACACB (0.52) | ACACB | |
| SCHEMBL9189969 | 0.72 | ALOX5 (0.43) | FFAR1PTGESACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468281-B1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | GRUENENTHAL GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |
| EP-0468281-A1 | Substituted phenylacetylenes, pharmaceuticals containing them and methods for the preparation of these compounds and pharmaceuticals | Grünenthal GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |