Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192702 | 0.85 | LMNA (0.31) | PIK3CGLMNAKDM4EALDH1A1 | |
| SCHEMBL9196786 | 0.72 | HCAR2 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL9190063 | 0.68 | PIK3CG (0.36) | PIK3CGLMNAKDM4EALDH1A1 | |
| SCHEMBL9191949 | 0.66 | ADORA2A (0.49) | — | |
| SCHEMBL9193394 | 0.63 | NOS1 (0.41) | PIK3CGLMNA | |
| SCHEMBL12457565 | 0.61 | LMNA (0.35) | LMNA | |
| SCHEMBL9197090 | 0.60 | ADORA2A (0.45) | KDM4EALDH1A1 | |
| SCHEMBL21994423 | 0.60 | KDM4E (0.34) | KDM4E | |
| Isoxanthopterin SCHEMBL4389432 | 0.60 | PIK3CG (0.46) | PIK3CGLMNAKDM4EALDH1A1 | |
| SCHEMBL22056025 | 0.60 | ENPP2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | disclosed |
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | disclosed |