Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 18/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493018 | 0.82 | FDPS (0.54) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL24616674 | 0.73 | FDPS (0.48) | FDPSPDE3ALMNAADRB3PDE4D | |
| Pamidronic Acid SCHEMBL18361 | 0.72 | FDPS (1.00) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL5293608 | 0.72 | — | — | |
| SCHEMBL28355003 | 0.72 | FDPS (0.47) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL12570894 | 0.71 | FDPS (0.56) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL24616673 | 0.71 | FDPS (0.68) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7035721 | 0.71 | FDPS (0.46) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL7032261 | 0.71 | FDPS (0.46) | FDPSPDE3ALMNAADRB3PDE4D | |
| Pamidronic Acid SCHEMBL8850008 | 0.70 | FDPS (0.95) | FDPSPDE3ALMNAADRB3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032784-A1 | PLATINUM ISOTOPE COMBINED WITH BONE-TARGETING AGENTS FOR USE IN ANTICANCER DRUGS | NUCLEAR RESEARCH AND CONSULTANCY GROUP (NL) | 2021-02-25 | — | — | WO | disclosed |
| EP-0444038-B1 | CONJUGATES FOR BONE IMAGING AND BONE CANCER THERAPY | NEORX CORP (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5202109-A | Conjugates for bone imaging and bone cancer therapy | NEORX CORPORATION (US) | 1993-04-13 | — | — | US | disclosed |
| US-5089249-A | CONJUGATES FOR BONE IMAGING AND BONE CANCER THERAPY | NEORX CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0444038-A1 | CONJUGATES FOR BONE IMAGING AND BONE CANCER THERAPY. | NEORX CORP (US) | 1991-09-04 | — | — | EP | disclosed |