Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.65 |
| ▸ | TUBB | P07437 | 4/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.65 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190495 | 1.00 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8575456 | 0.89 | PTGS2 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8575451 | 0.89 | PTGS2 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9188784 | 0.86 | PTGS2 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9188791 | 0.86 | PTGS2 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9188399 | 0.82 | TUBB1 (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9188404 | 0.82 | TUBB1 (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9185811 | 0.80 | PTGS2 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11692696 | 0.80 | S100B (0.66) | PTGS2ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL11692701 | 0.80 | S100B (0.66) | PTGS2ALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430062-A | Combretastatin analogues; inhibition of tubulin polymerization and colchicine binding; antitumor,-mitotic and -neoplastic agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1993023357-A1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-11-25 | — | — | WO | disclosed |