Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.42 |
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160503 | 0.76 | MAPT (0.42) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL6976927 | 0.74 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL596451 | 0.73 | MEN1 (0.43) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL14185382 | 0.72 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL145904 | 0.72 | MAPT (0.49) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL11181047 | 0.72 | MEN1 (0.43) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL7593051 | 0.72 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL7864240 | 0.71 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL3294487 | 0.69 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL8415311 | 0.69 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430065-B1 | Barbiturate assay compositions and methods | ABBOTT LAB (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5099020-A | Immunoassay with fluorescent compounds | ABBOTT LABORATORIES (US) | 1992-03-24 | — | — | US | disclosed |
| US-5096838-A | Fluorescent tracers for detection of barbiturates and for antiserums | ABBOTT LABORATORIES (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0430065-A2 | Barbiturate assay compositions and methods | ABBOTT LABORATORIES (US) | 1991-06-05 | — | — | EP | disclosed |