Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | MEN1 | O00255 | 11/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596451 | 0.83 | MEN1 (0.43) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9084677 | 0.82 | TSHR (0.55) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL12133543 | 0.79 | POLB (0.37) | MAPTALDH1A1POLBPKMLMNA | |
| SCHEMBL14185382 | 0.75 | MEN1 (0.46) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL145904 | 0.75 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9085470 | 0.74 | ALDH1A1 (0.50) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9190604 | 0.74 | MEN1 (0.42) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL7864240 | 0.74 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL3294487 | 0.72 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL13629854 | 0.72 | TSHR (0.68) | MEN1KMT2AALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199533-A1 | Novel amino carboxy alkyl derivatives of barbituric acid | CURRY KENNETH (CA) | 2003-10-23 | — | — | US | disclosed |
| EP-1276727-A1 | NOVEL AMINO CARBOXY ALKYL DERIVATIVES OF BARBITURIC ACID | Curry, Kenneth (CA) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001079185-A1 | NOVEL AMINO CARBOXY ALKYL DERIVATIVES OF BARBITURIC ACID | CURRY KENNETH (CA) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199533-A1 | Novel amino carboxy alkyl derivatives of barbituric acid | GRM1, GRM3, GRM2 | MAPT 2513/4885MEN1 3611/4885KMT2A 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.