Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547493 | 0.89 | ALDH1A1 (0.51) | ALDH1A1GAATDP1NPSR1L3MBTL1 | |
| SCHEMBL23468470 | 0.84 | MEN1 (0.40) | ALDH1A1GAATDP1KCNA3NPSR1 | |
| SCHEMBL1408147 | 0.84 | MEN1 (0.42) | ALDH1A1GAATDP1KCNA3NPSR1 | |
| SCHEMBL3342781 | 0.84 | CNR2 (0.48) | ALDH1A1GAATDP1NPSR1KMT2A | |
| SCHEMBL6326806 | 0.82 | NPC1 (0.53) | ALDH1A1GAANPSR1NPC1POLB | |
| SCHEMBL547411 | 0.82 | TDP1 (0.47) | ALDH1A1GAATDP1NPSR1L3MBTL1 | |
| SCHEMBL202173 | 0.82 | TDP1 (0.50) | ALDH1A1TDP1NPSR1L3MBTL1KMT2A | |
| SCHEMBL547806 | 0.81 | TDP1 (0.43) | ALDH1A1GAATDP1NPSR1L3MBTL1 | |
| SCHEMBL4744062 | 0.81 | NPC1 (0.55) | ALDH1A1NPC1HTTRAB9ATP53 | |
| SCHEMBL10956818 | 0.81 | NPC1 (0.55) | ALDH1A1NPC1HTTRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399184-B1 | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | ABBOTT LAB (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5354693-A | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassy | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| US-5248791-A | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5101015-A | Nitrogen-functional-group-containing immunogen | ABBOTT LABORATORIES (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0399184-A2 | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1990-11-28 | — | — | EP | disclosed |