SCHEMBL202173

SCHEMBL202173

O=C(O)CN(CC(=O)O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
NPSR1 Q6W5P4 2/20 0.48
KMT2A Q03164 4/20 0.45
ALDH1A1 P00352 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
TSHR P16473 2/20 0.45
POLB P06746 1/20 0.45
HTT P42858 1/20 0.45
GLA P06280 1/20 0.45
AKR1B1 P15121 1/20 0.42
MEN1 O00255 3/20 0.41
NOX1 Q9Y5S8 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
PLA2G2A P14555 1/20 0.40
BLM P54132 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11729646 0.91 TDP1 (0.47) TDP1NPSR1KMT2AALDH1A1NPC1
SCHEMBL547411 0.91 TDP1 (0.47) TDP1NPSR1KMT2AALDH1A1NPC1
SCHEMBL8038936 0.90 TDP1 (0.44) TDP1KMT2AALDH1A1NPC1RAB9A
SCHEMBL13644987 0.89 TDP1 (0.47) TDP1NPSR1KMT2AALDH1A1NPC1
SCHEMBL5983797 0.88 TDP1 (0.42) TDP1NPSR1KMT2AALDH1A1NPC1
SCHEMBL3838525 0.88 TDP1 (0.46) TDP1NPSR1KMT2AALDH1A1NPC1
SCHEMBL1132513 0.87 ALDH1A1 (0.53) TDP1NPSR1KMT2AALDH1A1NPC1
SCHEMBL27336574 0.87 TDP1 (0.44) TDP1NPSR1KMT2AALDH1A1NPC1
SCHEMBL13644999 0.87 LMNA (0.50) TDP1KMT2AALDH1A1NPC1RAB9A
SCHEMBL340808 0.86 CRHBP (0.47) TDP1NPSR1KMT2AALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 778 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3162868-B1 THERMAL BASE GENERATOR, THERMOSETTING RESIN COMPOSITION, CURED FILM, CURED FILM MANUFACTURING METHOD, AND SEMICONDUCTOR DEVICE FUJIFILM CORP (JP) 2022-10-05 EP claimed
CN-112080769-B Gold plating process for acoustic shielding cover 上海广弘实业有限公司 2022-06-14 CN claimed
CN-112080769-A Gold plating process for acoustic shielding cover 上海广弘实业有限公司 2020-12-15 CN claimed
CN-108948050-B Metal complex, preparation method thereof and bleaching working solution 浙江理工大学 2020-11-03 CN claimed
US-10315185-B2 Polyfunctional sorbent materials UNIVERSITY OF OREGON (US) 2019-06-11 US claimed
EP-2508611-B1 Process for production of triprenyl phenol compounds TMS CO LTD (JP) 2019-05-08 EP claimed
CN-106471089-B Thermokalite producing agent, thermosetting resin composition and application thereof 富士胶片株式会社 2018-10-19 CN claimed
CN-106317353-B A kind of phenol-formaldehyde resin modified and preparation method thereof of energy in-situ preparation graphene 武汉科技大学 2018-09-14 CN claimed
US-20180015442-A1 POLYFUNCTIONAL SORBENT MATERIALS UNIVERSITY OF OREGON (US) 2018-01-18 US claimed
CN-107226892-A A kind of phenol-formaldehyde resin modified of energy in-situ preparation CNT and preparation method thereof 武汉燃控碳烯科技有限公司 2017-10-03 CN claimed
EP-0130482-B1 DIAMINOCYCLOHEXANE PLATINUM COMPLEXES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Research Corporation (US) 1988-12-28 EP claimed
US-4758588-A Diaminocyclohexane platinum complexes RESEARCH CORPORATION TECHNOLOGIES (US) 1988-07-19 US claimed
EP-0223613-A2 Compounds that selectively bind sodium AMERSHAM INTERNATIONAL plc (GB) 1987-05-27 EP claimed
US-4661516-A WATER SOLUBLE, ANTITUMOR AGENTS RESEARCH CORPORATION (US) 1987-04-28 US claimed
EP-0130482-A1 Diaminocyclohexane platinum complexes, process for preparing same and pharmaceutical compositions containing same Research Corporation (US) 1985-01-09 EP claimed
US-4427762-A DEVELOPMENT WITH ALKALINE DEVELOPER MIXTURE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-01-24 US claimed
EP-0082015-A1 Method of forming an image with a photographic cuprous halide material KONICA CORPORATION (JP) 1983-06-22 EP claimed
US-4285575-A USING AN ELECTROCHROMIC ELECTROLYTE CONTAINING A CARBOXYLIC-CONTAINING COMPLEXING AGENT, A FERROUS SALT, A METAL SALT, AND A CHROMOGEN; DURABILITY CANON KABUSHIKI KAISHA (JP) 1981-08-25 US claimed
US-4212518-A ELECTROCHROMIC CELL CANON KABUSHIKI KAISHA (JP) 1980-07-15 US claimed
US-3984522-A Method of removing nitrogen monoxide from a nitrogen monoxide-containing gas ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-10-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180015442-A1 POLYFUNCTIONAL SORBENT MATERIALS EPCAM, SELPLG, SPR TDP1 2825/4885NPSR1 497/4885KMT2A 765/4885
US-10315185-B2 Polyfunctional sorbent materials EPCAM, SELPLG, SPR TDP1 2825/4885NPSR1 497/4885KMT2A 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.