Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202173 | 0.91 | TDP1 (0.50) | TDP1ALDH1A1NPSR1KMT2ANPC1 | |
| SCHEMBL11729646 | 0.86 | TDP1 (0.47) | TDP1ALDH1A1NPSR1KMT2ANPC1 | |
| SCHEMBL547493 | 0.85 | ALDH1A1 (0.51) | TDP1ALDH1A1NPSR1KMT2ANPC1 | |
| SCHEMBL487259 | 0.83 | TSHR (0.44) | TDP1ALDH1A1NPSR1KMT2ANPC1 | |
| SCHEMBL27336574 | 0.83 | TDP1 (0.44) | TDP1ALDH1A1NPSR1KMT2ANPC1 | |
| SCHEMBL1132513 | 0.83 | ALDH1A1 (0.53) | TDP1ALDH1A1NPSR1KMT2ANPC1 | |
| SCHEMBL28538693 | 0.83 | CA2 (0.43) | TDP1ALDH1A1POLBCYP3A4L3MBTL1 | |
| SCHEMBL9191007 | 0.82 | ALDH1A1 (0.43) | TDP1ALDH1A1NPSR1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8226907 | 0.81 | ALDH1A1 (0.52) | TDP1ALDH1A1NPSR1KMT2ANPC1 | |
| SCHEMBL547806 | 0.81 | TDP1 (0.43) | TDP1ALDH1A1NPSR1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508611-B1 | Process for production of triprenyl phenol compounds | TMS CO LTD (JP) | 2019-05-08 | — | — | EP | claimed |
| EP-2604697-B1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2015-07-01 | — | — | EP | claimed |
| EP-2604697-A1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | Tokyo University of Agriculture and Technology TLO (JP) | 2013-06-19 | — | — | EP | claimed |
| EP-2508611-B1 | Process for production of triprenyl phenol compounds | TMS CO LTD (JP) | 2019-05-08 | — | — | EP | disclosed |
| EP-2604697-B1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-8883462-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2000540-B1 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2604697-A1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | Tokyo University of Agriculture and Technology TLO (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2508611-A1 | Process for production of triprenyl phenol compounds | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2012-10-10 | — | — | EP | disclosed |
| US-20120100579-A1 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-8110596-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2009-08-27 | — | — | US | disclosed |
| EP-2000540-A9 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-2000540-A2 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | PLAT, F2R, F12 | TDP1 996/4885ALDH1A1 3251/4885NPSR1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.