SCHEMBL919129

SCHEMBL919129

CCCCCCCCCCCCCCCCCCCCCCCCC(CCCCCCCCCCCCCCCC)(CCCCCCCCCCCCCCCCCCCC)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.48
GPR84 Q9NQS5 7/20 0.48
PPARG P37231 7/20 0.48
PPARD Q03181 7/20 0.48
PPARA Q07869 7/20 0.48
HDAC11 Q96DB2 5/20 0.48
TSHR P16473 4/20 0.48
PTPN1 P18031 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48
ALOX15 P16050 1/20 0.48
PDE4A P27815 1/20 0.48
KMT2A Q03164 1/20 0.48
PDE3A Q14432 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8622832 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL2706070 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL2542583 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL160169 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL7087196 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL3242443 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL989797 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL5408758 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL22092533 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA
SCHEMBL459797 1.00 CES2 (0.48) CES2GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1752136-B1 Cosmetic mascara compositions for lengthening lashes OREAL (FR) 2014-03-05 EP claimed
US-7871634-B2 mascara compositions containing an aqueous phase, fatty phase, a structuring agent, and a polyurethane/poly(meth)acrylate graft copolymer; softness and evenness of film deposited on the lashes, improved separation and longer wear L'ORÉAL (FR) 2011-01-18 US claimed
EP-1345632-B1 ABSORBENT ARTICLES WITH NON-AQUEOUS COMPOSITIONS CONTAINING BOTANICALS KIMBERLY CLARK CO (US) 2010-02-17 EP claimed
EP-1455722-B1 SYSTEM FOR SKIN HEALTH OF ABSORBENT ARTICLE WEARERS KIMBERLY CLARK CO (US) 2008-01-16 EP claimed
US-20070036739-A1 mascara compositions containing an aqueous phase, fatty phase, a structuring agent, and a polyurethane/poly(meth)acrylate graft copolymer; softness and evenness of film deposited on the lashes, improved separation and longer wear L'OREAL (FR) 2007-02-15 US claimed
EP-1752136-A2 Cosmetic compositions useful for lengthening lashes L'Oréal (FR) 2007-02-14 EP claimed
US-20260021219-A1 METHODS AND ABSORBENT ARTICLES FOR INHIBITING FECAL PROTEASE ACTIVITY KIMBERLY CLARK CO (US) 2026-01-22 US disclosed
WO-2024073721-A1 METHODS AND ABSORBENT ARTICLES FOR INHIBITING FECAL PROTEASE ACTIVITY KIMBERLY-CLARK WORLDWIDE, INC. (US) 2024-04-04 WO disclosed
US-10265434-B2 Absorbent articles comprising glyceride copolymers THE PROCTER & GAMBLE COMPANY (US) 2019-04-23 US disclosed
US-20180161474-A1 ABSORBENT ARTICLES COMPRISING GLYCERIDE COPOLYMERS THE PROCTER & GAMBLE COMPANY 2018-06-14 US disclosed
WO-2018013151-A1 ABSORBENT ARTICLES COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS THE PROCTER & GAMBLE COMPANY (US) 2018-01-18 WO disclosed
US-20180008484-A1 ABSORBENT ARTICLES COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS THE PROCTER & GAMBLE COMPANY 2018-01-11 US disclosed
US-8173143-B2 Personal skin care compositions containing anti-flammatory and anti-microbial agents JORMAY, INC. 2012-05-08 US disclosed
US-20030130635-A1 Absorbent articles with compositions having even distribution KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-10 US disclosed
WO-2003053486-A1 ABSORBENT ARTICLE COMPRISING A YUCCA EXTRACT KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-07-03 WO disclosed
US-20030120228-A1 Absorbent article KIMBERLY-CLARK WORLDWIDE, INC. 2003-06-26 US disclosed
US-20020136755-A1 Absorbent articles with non-aqueous compositions containing botanicals KIMBERLY-CLARK WORLDWIDE, INC. 2002-09-26 US disclosed
US-20020128615-A1 Absorbent articles with non-aqueous compositions containing anionic polymers KIMBERLY-CLARK WORLDWIDE, INC. 2002-09-12 US disclosed
WO-2002060502-A2 ABSORBENT ARTICLES WITH NON-AQUEOUS COMPOSITIONS CONTAINING ANIONIC POLYMERS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2002-08-08 WO disclosed
WO-2002051456-A2 ABSORBENT ARTICLES WITH NON-AQUEOUS COMPOSITIONS CONTAINING BOTANICALS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2002-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021219-A1 METHODS AND ABSORBENT ARTICLES FOR INHIBITING FECAL PROTEASE ACTIVITY CUTA, CTRL, PEPD CES2 653/4885GPR84 3228/4885PPARG 4198/4885
US-20070036739-A1 mascara compositions containing an aqueous phase, fatty phase, a structuring agent, and a polyurethane/poly(meth)acrylate graft copolymer; softness and evenness of film deposited on the lashes, improved separation and longer wear ABHD16A, ABHD6, MATR3 CES2 190/4885GPR84 3200/4885PPARG 2127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.