SCHEMBL9192003

SCHEMBL9192003

[N]N(c1cccc2c1C(=O)c1ccccc1C2=O)c1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 7/20 0.67
ALDH1A1 P00352 7/20 0.67
MAPT P10636 6/20 0.67
MAPK1 P28482 6/20 0.67
TDP1 Q9NUW8 3/20 0.67
EGFR P00533 3/20 0.67
NSD2 O96028 1/20 0.67
LMNA P02545 1/20 0.67
MEN1 O00255 5/20 0.57
KMT2A Q03164 5/20 0.57
PABPC1 P11940 3/20 0.57
KDM4E B2RXH2 2/20 0.53
ADORA2A P29274 2/20 0.52
CDC25B P30305 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
RAB9A P51151 3/20 0.47
MAOA P21397 6/20 0.46
PTK2B Q14289 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ALOX12 P18054 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9393651 0.80 MAPT (0.67) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL9844713 0.80 ALDH1A1 (0.79) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL11225143 0.80 ALDH1A1 (0.67) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL187706 0.80 L3MBTL1 (1.00) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL9442045 0.79 L3MBTL1 (0.61) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL7170509 0.78 L3MBTL1 (0.70) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL11316550 0.77 MAPT (0.62) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL2062965 0.77 ALDH1A1 (0.62) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL28208845 0.77 ALDH1A1 (0.73) L3MBTL1ALDH1A1MAPTMAPK1TDP1
SCHEMBL15453236 0.77 L3MBTL1 (0.62) L3MBTL1ALDH1A1MAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4374989-A Process for the manufacture of dianthraquinonyl-N,N'-dihydroazine CIBA-GEIGY AG (CH) 1983-02-22 US claimed
EP-0572854-B1 Process for the preparation of dianthraquinonyl-N,N'-dihydroazine and of its chlorinated derivatives BASF AG (DE) 1995-11-08 EP disclosed
EP-0572854-A1 Process for the preparation of dianthraquinonyl-N,N'-dihydroazine and of its chlorinated derivatives BASF Aktiengesellschaft (DE) 1993-12-08 EP disclosed
US-4374989-A Process for the manufacture of dianthraquinonyl-N,N'-dihydroazine CIBA-GEIGY AG (CH) 1983-02-22 US disclosed
US-4374989-A Process for the manufacture of dianthraquinonyl-N,N'-dihydroazine CIBA-GEIGY AG (CH) 1983-02-22 US disclosed
US-4374989-A Process for the manufacture of dianthraquinonyl-N,N'-dihydroazine CIBA-GEIGY AG (CH) 1983-02-22 US disclosed