Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.48 |
| ▸ | NPC1 | O15118 | 11/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566168 | 0.81 | FAAH (0.39) | — | |
| SCHEMBL8846309 | 0.79 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8846166 | 0.77 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9190865 | 0.77 | MMP1 (0.40) | RAB9ANPC1KDM4ETDP1KMT2A | |
| SCHEMBL9566090 | 0.77 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9253964 | 0.76 | MMP1 (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8846207 | 0.76 | AKR1C3 (0.33) | — | |
| SCHEMBL9190928 | 0.76 | AKR1C3 (0.33) | — | |
| SCHEMBL9580375 | 0.74 | — | — | |
| SCHEMBL9566137 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547972-A1 | Heterocyclic amide derivatives and their use as pesticides | ROUSSEL-UCLAF (FR) | 1993-06-23 | — | — | EP | claimed |
| EP-0547972-B1 | Heterocyclic amide derivatives and their use as pesticides | ROUSSEL UCLAF (FR) | 1995-03-22 | — | — | EP | disclosed |
| EP-0547972-A1 | Heterocyclic amide derivatives and their use as pesticides | ROUSSEL-UCLAF (FR) | 1993-06-23 | — | — | EP | disclosed |