Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA5A | P35218 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191559 | 0.91 | ALOX15 (0.34) | ALOX15TSHRALDH1A1ALOX5HPGD | |
| SCHEMBL9550210 | 0.79 | ALDH1A1 (0.38) | TSHRALDH1A1ALOX5HPGDPTGS2 | |
| SCHEMBL9550244 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1DHODHMEN1MAPTKMT2A | |
| SCHEMBL9196621 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1DHODHMEN1MAPTKMT2A | |
| SCHEMBL9586849 | 0.69 | ALDH1A1 (0.49) | ALDH1A1ALOX5HPGDCA12CA1 | |
| SCHEMBL9364842 | 0.69 | ALDH1A1 (0.49) | ALDH1A1ALOX5HPGDCA12CA1 | |
| SCHEMBL9550224 | 0.65 | — | — | |
| SCHEMBL9031045 | 0.64 | MAPK8 (0.38) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL9469498 | 0.64 | MAPK8 (0.38) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL9550223 | 0.64 | GRM1 (0.54) | ALDH1A1MEN1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471262-B1 | Process for the production of substituted 3-amino-acrylesters | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| US-5196541-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-AMINOACRYLIC ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0471262-A1 | Process for the production of substituted 3-amino-acrylesters | BAYER AG (DE) | 1992-02-19 | — | — | EP | disclosed |