Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863918 | 0.99 | PTPN11 (0.43) | PTPN11PTPN1PTPN6NR5A1RARB | |
| SCHEMBL13863862 | 0.90 | CSNK2A1 (0.39) | NPC1RAB9ATP53MEN1GAA | |
| SCHEMBL91923 | 0.89 | PTPN11 (0.39) | PTPN11PTPN1PTPN6NR5A1RARB | |
| SCHEMBL91876 | 0.86 | THRB (0.44) | PTPN11NR5A1RARBPLA2G2ATSHR | |
| SCHEMBL91942 | 0.84 | RARB (0.47) | PTPN11PTPN1PTPN6NR5A1RARB | |
| SCHEMBL13863920 | 0.83 | RARB (0.39) | PTPN11PTPN1PTPN6NR5A1RARB | |
| SCHEMBL13863933 | 0.81 | PTPN11 (0.33) | PTPN11PTPN1PTPN6NR5A1RARB | |
| SCHEMBL91912 | 0.79 | PLA2G2A (0.39) | NR5A1RARBPLA2G2ATSHRLTA4H | |
| SCHEMBL13863876 | 0.79 | PLA2G2A (0.39) | NR5A1RARBPLA2G2ATSHRLTA4H | |
| SCHEMBL13863811 | 0.79 | PLA2G2A (0.39) | NR5A1RARBPLA2G2ATSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |