Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786008 | 0.88 | PLA2G2A (0.56) | RARBPLA2G2ANR5A1TSHRCYP3A4 | |
| SCHEMBL2090755 | 0.88 | PLA2G2A (0.56) | RARBPLA2G2ANR5A1TSHRCYP3A4 | |
| SCHEMBL91866 | 0.88 | PLA2G2A (0.42) | RARBPLA2G2ANR5A1TSHRPTPN11 | |
| SCHEMBL13863918 | 0.85 | PTPN11 (0.43) | RARBPLA2G2ANR5A1TSHRCYP3A4 | |
| SCHEMBL91924 | 0.84 | PTPN11 (0.41) | RARBPLA2G2ANR5A1TSHRPTPN11 | |
| SCHEMBL91876 | 0.84 | THRB (0.44) | RARBPLA2G2ANR5A1TSHRPTPN11 | |
| SCHEMBL9552950 | 0.83 | CYP2D6 (0.59) | RARBCYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL18886699 | 0.77 | PLA2G2A (0.68) | PLA2G2ANR5A1TSHRCYP3A4BLM | |
| SCHEMBL9016884 | 0.77 | PLA2G2A (0.68) | PLA2G2ANR5A1TSHRCYP3A4BLM | |
| SCHEMBL15823450 | 0.77 | ALDH1A1 (0.61) | RARBTSHRCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |