Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184469 | 0.89 | LIPG (0.46) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL25786683 | 0.89 | LIPG (0.46) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9350709 | 0.87 | LIPG (0.50) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL25031389 | 0.85 | LIPG (0.47) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9187793 | 0.84 | LIPG (0.40) | LIPGCYP3A4L3MBTL1CYSLTR2CYSLTR1 | |
| SCHEMBL9418574 | 0.79 | LIPG (0.56) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL6859975 | 0.79 | L3MBTL1 (0.48) | ALDH1A1TP53HSP90AA1CYP3A4THRB | |
| SCHEMBL10869653 | 0.79 | LIPG (0.56) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL14785526 | 0.79 | LIPG (0.56) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL1567827 | 0.79 | LIPG (0.56) | LIPGBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667887-A1 | DYES | ZENECA LIMITED (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010248-A1 | DYES | ZENECA LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |