Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25031389 | 0.98 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL9192542 | 0.87 | LIPG (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL13689141 | 0.85 | ADRA2B (0.42) | THRB | |
| SCHEMBL25786683 | 0.85 | LIPG (0.46) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL9184469 | 0.85 | LIPG (0.46) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL31390779 | 0.85 | TDP1 (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL14191957 | 0.85 | TDP1 (0.47) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL9418574 | 0.82 | LIPG (0.56) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL10869653 | 0.82 | LIPG (0.56) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL1567827 | 0.82 | LIPG (0.56) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314314-B1 | Filled compositions | DOW CORNING SA (BE) | 1994-08-24 | — | — | EP | disclosed |
| US-5073586-A | Polysiloxane, carbonate, alkylsulfonate, low modulus | DOW CORNING S.A. (BE) | 1991-12-17 | — | — | US | disclosed |
| EP-0314314-A2 | Filled compositions | DOW CORNING S.A. (BE) | 1989-05-03 | — | — | EP | disclosed |