Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.92 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.92 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | BCHE | P06276 | 2/20 | 0.72 |
| ▸ | ACHE | P22303 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.70 |
| ▸ | MPO | P05164 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | NQO2 | P16083 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759323 | 0.96 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL7024067 | 0.87 | MTNR1A (0.70) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL9295682 | 0.85 | MTNR1A (0.76) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL4859320 | 0.85 | KDM4E (1.00) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL7020873 | 0.84 | SPR (0.91) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL12720722 | 0.83 | MTNR1A (0.78) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL25210031 | 0.83 | KDM4E (1.00) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| Melatonin SCHEMBL4686085 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| Melatonin SCHEMBL29349848 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL23644935 | 0.83 | MTNR1A (0.83) | MTNR1AMTNR1BALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527687-B1 | Novel arylethylamin derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-11-22 | — | — | EP | claimed |
| US-5276051-A | Treatment of melatoninergic system, antiischemic agents and skin disorders using aminoalkylindole compounds | ADIR ET COMPAGNIE (FR) | 1994-01-04 | — | — | US | claimed |
| EP-0527687-A2 | Novel arylethylamin derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-17 | — | — | EP | claimed |