Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548851 | 0.80 | TDP1 (0.56) | TDP1L3MBTL1CES1CES2ATM | |
| SCHEMBL1492635 | 0.80 | CES1 (0.57) | TDP1L3MBTL1CES1CES2ATM | |
| SCHEMBL2358014 | 0.80 | ATM (0.64) | TDP1L3MBTL1CES1CES2ATM | |
| SCHEMBL2238176 | 0.80 | TDP1 (0.56) | TDP1L3MBTL1CES1CES2ATM | |
| SCHEMBL24188 | 0.80 | TDP1 (0.56) | TDP1L3MBTL1CES1CES2ATM | |
| SCHEMBL29170482 | 0.79 | CES2 (0.52) | CES1CES2LMNANPC1RAB9A | |
| SCHEMBL2319435 | 0.79 | CES2 (0.52) | CES1CES2LMNANPC1RAB9A | |
| SCHEMBL10361690 | 0.79 | CES2 (0.52) | L3MBTL1CES1CES2ATMGAA | |
| SCHEMBL2379357 | 0.78 | CES1 (0.58) | TDP1L3MBTL1CES1CES2ATM | |
| Hydrochloric Acid SCHEMBL27977560 | 0.78 | TDP1 (0.54) | TDP1L3MBTL1CES1CES2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248354-A | Synthetic method of fluoroacetophenone | 山东国邦药业有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-102285967-A | 2-arylmethylmercapto-6-(tetrahydroquinoline-1-methyl)-4-pyrimidone derivatives, and preparation method and use thereof | — | 2011-12-21 | — | — | CN | claimed |
| CN-114213630-B | Mannich modified amine epoxy resin curing agent and preparation method thereof | 上海船舶工艺研究所(中国船舶集团有限公司第十一研究所) | 2024-04-05 | — | — | CN | disclosed |
| CN-116693375-B | Synthesis method of 2, 4-dichloro-5-fluoro acetophenone | 山东国邦药业有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116554012-B | Synthetic method for preparing 2, 4-dichloro-5-fluoro acetophenone by using polysubstituted impurities | 山东国邦药业有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116693375-A | Synthesis method of 2, 4-dichloro-5-fluoro acetophenone | 山东国邦药业有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116554012-A | Synthetic method for preparing 2, 4-dichloro-5-fluoro acetophenone by using polysubstituted impurities | 山东国邦药业有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-115626868-A | Method for synthesizing fluochloroacetophenone by solid acid catalysis | 山东国邦药业有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115626868-A | Method for synthesizing fluochloroacetophenone by solid acid catalysis | 山东国邦药业有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-113248354-B | Synthetic method of fluoroacetophenone | 山东国邦药业有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114213630-A | Mannich modified amine epoxy resin curing agent and preparation method thereof | 上海船舶工艺研究所(中国船舶工业集团公司第十一研究所) | 2022-03-22 | — | — | CN | disclosed |
| CN-101429177-A | Process for producing bactericide of flutriafol midbody | JIANGSU SEVENCONTINENT GREEN C (CN) | 2009-05-13 | — | — | CN | disclosed |
| EP-0637306-A1 | 4-IMIDOMETHYL-1- 2'PHENYL-2'OXOETHYL-] PIPERIDINES AS SEROTONIN 5HT 2?-ANTAGONISTS, THEIR PREPARATION AND USE IN THERAPY | MERRELL PHARMACEUTICALS INC. (US) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022309-A1 | 4-IMIDOMETHYL-1-[2'PHENYL-2'OXOETHYL-] PIPERIDINES AS SEROTONIN 5HT2-ANTAGONISTS, THEIR PREPARATION AND USE IN THERAPY | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-11-11 | — | — | WO | disclosed |
| CN-1067892-A | The preparation method of new pyrrolo-[2,3-b] pyridine derivate | ASTRA AB (SE) | 1993-01-13 | — | — | CN | disclosed |
| CN-1019109-B | The insect-killing composition that contains diphenyl ether derivatives pesticide compound | ICI PLC (GB) | 1992-11-18 | — | — | CN | disclosed |
| CN-1013857-B | PROCESS FOR PREPARATION OF DIPHENYL OXIDE COMPOUNDS WITH INSECTICIDALL ACTIVITY | ICI PLC (GB) | 1991-09-11 | — | — | CN | disclosed |
| CN-88100991-A | Be used to prepare the method and the intermediate of compound with insecticidal activity | — | 1988-08-31 | — | — | CN | disclosed |
| EP-0153803-A2 | Triazole antifungal agents | Pfizer Limited (GB) | 1985-09-04 | — | — | EP | disclosed |
| US-3991202-A | ANTIMICROBIALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |