Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28083730 | 0.93 | HSD17B10 (0.59) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL92781 | 0.91 | SMN1; SMN2 (0.61) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT | |
| Bromide SCHEMBL10996884 | 0.89 | SMN1; SMN2 (0.59) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL2170235 | 0.81 | SMN1; SMN2 (0.54) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL9192703 | 0.78 | FBP1 (0.49) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL31359187 | 0.76 | HSD17B10 (0.72) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL10151628 | 0.76 | RAB9A (0.66) | HSD17B10SMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL464409 | 0.76 | HSD17B10 (0.72) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL12810173 | 0.76 | SMN1; SMN2 (0.53) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL1133153 | 0.76 | SMN1; SMN2 (0.57) | HSD17B10SMN1; SMN2RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383092-B1 | Chromogenic merocyanine enzyme substrates | BAYER AG (US) | 1995-12-13 | — | — | EP | disclosed |
| US-5191073-A | Indicators for colorimetric analysis of enzymes | MILES INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5122602-A | Optical indicators; medical diagnosis; quantitative analysis; immunoassay | MILES INC. (US) | 1992-06-16 | — | — | US | disclosed |
| EP-0383092-A2 | Chromogenic merocyanine enzyme substrates | Bayer Corporation (US) | 1990-08-22 | — | — | EP | disclosed |