SCHEMBL91946

SCHEMBL91946

O=C(Nc1ccc(S(=O)(=O)O)cc1)c1cccc(S(=O)(=O)C(Br)(Br)Br)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
ADORA3 P0DMS8 1/20 0.55
SLC6A3 Q01959 1/20 0.55
TIMP3 P35625 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
TDP1 Q9NUW8 1/20 0.51
MAOA P21397 1/20 0.51
MAOB P27338 1/20 0.51
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
MAPK1 P28482 1/20 0.50
TP53 P04637 1/20 0.50
HPGD P15428 1/20 0.50
ALDH1A1 P00352 2/20 0.49
STAT3 P40763 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PRMT1 Q99873 1/20 0.49
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14389426 0.87 MEN1 (0.60) MEN1KMT2AADORA3SLC6A3SMN1; SMN2
SCHEMBL14548345 0.86 MEN1 (0.66) MEN1KMT2AADORA3SLC6A3SMN1; SMN2
SCHEMBL14389498 0.81 MEN1 (0.65) MEN1KMT2ASMN1; SMN2LMNAGAA
SCHEMBL14389430 0.81 L3MBTL1 (0.68) MEN1KMT2AADORA3SLC6A3SMN1; SMN2
SCHEMBL7784153 0.80 SMN1; SMN2 (0.67) MEN1KMT2AADORA3SLC6A3SMN1; SMN2
SCHEMBL14389314 0.79 ALDH1A1 (0.51) MEN1KMT2ATIMP3SMN1; SMN2TDP1
SCHEMBL10528190 0.79 SMN1; SMN2 (0.58) MEN1KMT2AADORA3SLC6A3TIMP3
SCHEMBL10528203 0.79 PTGS1 (0.62) MEN1KMT2AADORA3SLC6A3TIMP3
SCHEMBL10035665 0.79 TIMP3 (0.62) MEN1KMT2ATIMP3SMN1; SMN2MAOA
SCHEMBL10797525 0.79 PTGS1 (0.62) MEN1KMT2ATIMP3SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219336-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-13 US disclosed
US-20230150254-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-05-18 US disclosed
US-20230142087-A1 LAMINATE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-8127675-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20100005989-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION 2010-01-14 US disclosed
EP-1557262-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2007-11-14 EP disclosed
US-20070092836-A1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-04-26 US disclosed