SCHEMBL919499

SCHEMBL919499

CCCCCCCC[SiH](C)C1CCCCO1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.39
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 1/20 0.34
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10982356 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL6907099 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL5694919 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL2902983 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL1464494 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL3220232 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL4274535 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL29233370 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL6414919 1.00 EPHX1 (0.39) EPHX1ALDH1A1TDP1CYP1A2NAAA
SCHEMBL6034964 0.98 EPHX1 (0.38) EPHX1ALDH1A1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577400-B2 Topical skin closure compositions and systems ETHICON, INC. (US) 2026-03-17 US claimed
US-12465577-B2 Antimicrobial topical skin closure compositions and systems ETHICON, INC. (US) 2025-11-11 US claimed
EP-2780425-B1 RAPID CURE SILICONE LUBRICIOUS COATINGS ETHICON INC (US) 2025-07-30 EP claimed
EP-4157374-B1 ANISOTROPIC WOUND CLOSURE SYSTEMS ETHICON INC (US) 2025-06-04 EP claimed
EP-4157520-B1 NOVEL TOPICAL SKIN CLOSURE COMPOSITIONS AND SYSTEMS ETHICON INC (US) 2025-03-26 EP claimed
EP-4157376-B1 NOVEL ANTIMICROBIAL TOPICAL SKIN CLOSURE COMPOSITIONS AND SYSTEMS ETHICON INC (US) 2025-03-05 EP claimed
US-11969524-B2 Low temperature cured silicone lubricious coatings ETHICON, INC. (US) 2024-04-30 US claimed
US-11839701-B2 Two-step batch process for coating surgical needles ETHICON, INC. (US) 2023-12-12 US claimed
US-20230348722-A1 Novel Topical Skin Closure Compositions and Systems ETHICON, INC. (US) 2023-11-02 US claimed
US-11718753-B2 Topical skin closure compositions and systems ETHICON, INC. (US) 2023-08-08 US claimed
EP-0787485-A2 Oil-in-water emulsion containing an anionic silicone surfactant, composition containing the same and its use in cosmetics, pharmacy or hygiene L'OREAL (FR) 1997-08-06 EP claimed
EP-0766708-A2 ORGANOMINERAL SILICATE COPOLYMER-BASED DETEREGENT BUILDER AND DETERGENT COMPOSITIONS CONTAINING SAME RHONE-POULENC CHIMIE (FR) 1997-04-09 EP claimed
EP-0583775-B1 Slipping layer binder for dye-donor element used in thermal dye transfer EASTMAN KODAK CO (US) 1996-12-11 EP claimed
WO-1995035338-A2 ORGANOMINERAL SILICATE COPOLYMER-BASED DETEREGENT BUILDER AND DETERGENT COMPOSITIONS CONTAINING SAME RHONE-POULENC CHIMIE (FR) 1995-12-28 WO claimed
US-5399602-A Nonswelling in contact with mineral oils DOW CORNING TORAY SILICONE, CO. LTD. (JP) 1995-03-21 US claimed
US-5374363-A Mixture of a polysiloxane as base oil, sulfur compound and a cyclic polysiloxane DOW CORNING ASIA, LTD. (JP) 1994-12-20 US claimed
EP-0600301-A1 Viscous coupling fluids DOW CORNING ASIA, Ltd. (JP) 1994-06-08 EP claimed
EP-0590595-A2 Oil-resistant silicone rubber composition Dow Corning Toray Silicone Company, Limited (JP) 1994-04-06 EP claimed
US-5192406-A Silica or glass capillaries bonded to polysiloxanes, polysilazanes or other silicone polymers for separation SUPELCO (US) 1993-03-09 US claimed
EP-0494544-A2 Deactivated capillary columns for use in electrophoresis and micellar electrokinetic chromatography S.A.C. CORPORATION (US) 1992-07-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465577-B2 Antimicrobial topical skin closure compositions and systems CUTA, DSG1, ERCC4 EPHX1 2136/4885ALDH1A1 4193/4885TDP1 2540/4885
US-12577400-B2 Topical skin closure compositions and systems CUTA, DSG1, CDH1 EPHX1 1411/4885ALDH1A1 4385/4885TDP1 1719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.