SCHEMBL9195355

SCHEMBL9195355

Clc1cc2scnc2c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
HSD17B10 Q99714 2/20 0.39
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
CCR1 P32246 1/20 0.37
CCR8 P51685 1/20 0.37
MAPT P10636 6/20 0.36
KDM4E B2RXH2 5/20 0.36
HTT P42858 4/20 0.36
LMNA P02545 4/20 0.36
HSP90AA1 P07900 4/20 0.36
MMP14 P50281 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TP53 P04637 2/20 0.36
CYP3A4 P08684 2/20 0.36
ALOX15 P16050 2/20 0.36
ALOX12 P18054 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080792 0.78 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP1A2CYP2A6L3MBTL1
SCHEMBL9190728 0.76 KDM4E (0.41) ALDH1A1HSD17B10MAPTKDM4EHTT
Hydrochloric Acid SCHEMBL6074189 0.76 MYC (0.43) ALDH1A1HSD17B10CYP1A2L3MBTL1MAPT
Hydrochloric Acid SCHEMBL6743143 0.76 MYC (0.43) ALDH1A1HSD17B10CYP1A2L3MBTL1MAPT
SCHEMBL9198393 0.74 ALDH1A1 (0.36) ALDH1A1HSD17B10CYP2A6L3MBTL1KDM4E
SCHEMBL4643388 0.74 MAPT (0.39) ALDH1A1HSD17B10MAPTKDM4EHTT
SCHEMBL9193166 0.74 ALDH1A1 (0.36) ALDH1A1HSD17B10
SCHEMBL24155399 0.71 CYP1A2 (0.41) ALDH1A1HSD17B10CYP1A2CYP2A6MAPT
SCHEMBL9125141 0.71 LMNA (0.40) ALDH1A1HSD17B10L3MBTL1MAPTKDM4E
SCHEMBL24156067 0.70 L3MBTL1 (0.38) ALDH1A1HSD17B10CYP1A2CYP2A6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0532798-B1 An electroluminescent element ASAHI CHEMICAL IND (JP) 1995-12-06 EP disclosed
US-5281489-A Anode, cathode, organic luminescent layer disposed between, the luminescent layer comprising a fluorescent luminescent agent, a hole moving and donating agent, an electron moving and donating agent ASASHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-01-25 US disclosed
EP-0532798-A1 An electroluminescent element ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-03-24 EP disclosed