Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28135695 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL29035793 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL28151606 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL910451 | 0.73 | LIPE (0.53) | SMN1; SMN2ALDH1A1KMT2AHTT | |
| SCHEMBL1257515 | 0.73 | ALDH1A1 (0.42) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL25669794 | 0.73 | HRH3 (0.50) | SMN1; SMN2PKMALDH1A1KMT2AHPGD | |
| SCHEMBL2960234 | 0.72 | ALDH1A1 (0.41) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL28066960 | 0.72 | ALDH1A1 (0.41) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL27621125 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL9194931 | 0.71 | HTT (0.45) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471983-B1 | Process for the N-alkylation of urea | CHEMIE LINZ GMBH (AT) | 1995-03-22 | — | — | EP | disclosed |
| EP-0471983-A1 | Process for the N-alkylation of urea | Chemie Linz GmbH (AT) | 1992-02-26 | — | — | EP | disclosed |