Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909405 | 0.84 | PPARD (0.49) | PPARDDRD2DRD3SLC6A9SRD5A1 | |
| SCHEMBL8409809 | 0.84 | SLC6A9 (0.50) | PPARDSLC6A9SRD5A1MTNR1ACYP19A1 | |
| SCHEMBL1844946 | 0.80 | PPARD (0.52) | PPARDDRD2DRD3SLC6A9SRD5A1 | |
| SCHEMBL1479951 | 0.78 | CYP19A1 (0.56) | PPARDSLC6A9SRD5A1MTNR1ACYP19A1 | |
| SCHEMBL10796511 | 0.78 | TRPV1 (0.41) | SRD5A1LMNA | |
| SCHEMBL22867687 | 0.77 | DRD2 (0.53) | DRD2DRD3SRD5A1CYP19A1LMNA | |
| SCHEMBL15157394 | 0.76 | LMNA (0.52) | PPARDSLC6A9SRD5A1CYP19A1LMNA | |
| SCHEMBL30563632 | 0.76 | DRD2 (0.58) | DRD2DRD3SRD5A1CYP19A1ACHE | |
| SCHEMBL26962573 | 0.76 | DRD2 (0.58) | DRD2DRD3SRD5A1CYP19A1ACHE | |
| SCHEMBL268865 | 0.76 | DRD2 (0.58) | DRD2DRD3SRD5A1CYP19A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637302-A1 | ARTHROPODICIDAL OXA- AND THIA-ZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-08 | — | — | EP | disclosed |