Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 7/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | GLI1 | P08151 | 1/20 | 0.36 |
| ▸ | GLI2 | P10070 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201144 | 1.00 | NPY1R (0.42) | NPY1RCNR1CNR2NPY5RNPFFR1 | |
| SCHEMBL1718512 | 0.94 | NPY1R (0.42) | NPY1RCNR1CNR2NPY5RNPFFR1 | |
| SCHEMBL9195693 | 0.90 | NPY1R (0.42) | NPY1RCNR1CNR2NPY5RNPFFR1 | |
| SCHEMBL9194825 | 0.89 | ALDH1A1 (0.42) | CNR1CNR2 | |
| SCHEMBL9194821 | 0.89 | ALDH1A1 (0.42) | CNR1CNR2 | |
| SCHEMBL1388287 | 0.88 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL8069325 | 0.85 | CNR1 (0.39) | NPY1RCNR1CNR2TRPV1 | |
| SCHEMBL8059066 | 0.85 | CNR1 (0.47) | NPY1RCNR1CNR2 | |
| SCHEMBL8070223 | 0.85 | CNR1 (0.39) | NPY1RCNR1CNR2NPY5RSLC6A5 | |
| SCHEMBL8073040 | 0.85 | NPY1R (0.41) | NPY1RCNR1NPY5RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |