Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 17/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28365189 | 0.71 | MAPT (0.56) | ALDH1A1HPGDHTTKMT2AMAPT | |
| SCHEMBL9198596 | 0.70 | ALDH1A1 (0.54) | ALDH1A1HPGDHTTKMT2AMAPT | |
| SCHEMBL21601113 | 0.70 | SIRT1 (1.00) | SIRT1ALDH1A1SIRT2SIRT5 | |
| SCHEMBL21601103 | 0.70 | SIRT1 (1.00) | SIRT1ALDH1A1SIRT2SIRT5 | |
| SCHEMBL17971664 | 0.69 | KMT2A (1.00) | ALDH1A1HPGDHTTKMT2AMAPT | |
| SCHEMBL12204697 | 0.68 | CYP19A1 (0.64) | ALDH1A1HPGDHTTKMT2AMAPT | |
| SCHEMBL21601054 | 0.68 | SIRT1 (0.63) | SIRT1ALDH1A1KMT2AMAPTSIRT2 | |
| SCHEMBL11964014 | 0.67 | KMT2A (0.63) | ALDH1A1HPGDHTTKMT2AMAPT | |
| SCHEMBL28561988 | 0.66 | KMT2A (0.69) | ALDH1A1HPGDHTTKMT2AMAPT | |
| SCHEMBL21601044 | 0.66 | SIRT1 (1.00) | SIRT1KMT2ASIRT2SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578849-B1 | Process for the preparation of 1,3-dioxane-4,6-dione derivates | BIOGAL GYOGYSZERGYAR (HU) | 1995-05-17 | — | — | EP | disclosed |
| EP-0578849-A1 | Process for the preparation of 1,3-dioxane-4,6-dione derivates | BIOGAL GYOGYSZERGYAR (HU) | 1994-01-19 | — | — | EP | disclosed |