Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495157 | 0.71 | GSK3B (0.46) | ALDH1A1KMT2AHPGDHTTADAMTS5 | |
| SCHEMBL17971664 | 0.70 | KMT2A (1.00) | ALDH1A1KMT2AHPGDHTTGSK3B | |
| SCHEMBL13848481 | 0.70 | KMT2A (0.60) | ALDH1A1KMT2AHPGDHTTADAMTS5 | |
| SCHEMBL9195778 | 0.70 | SIRT1 (0.54) | ALDH1A1KMT2AHPGDHTTMAPT | |
| SCHEMBL1587773 | 0.69 | ALDH1A1 (0.66) | ALDH1A1KMT2AHPGDHTTCRHBP | |
| SCHEMBL2074727 | 0.69 | ALDH1A1 (0.60) | ALDH1A1KMT2AHPGDHTTCRHBP | |
| SCHEMBL10990467 | 0.69 | ALDH1A1 (0.41) | ALDH1A1KMT2AHPGDCRHBPCRHR2 | |
| SCHEMBL30901197 | 0.69 | NR1I2 (0.63) | ALDH1A1KMT2AHPGDHTTADAMTS5 | |
| SCHEMBL30901196 | 0.69 | NR1I2 (0.63) | ALDH1A1KMT2AHPGDHTTADAMTS5 | |
| SCHEMBL15389049 | 0.68 | MAPT (0.43) | ALDH1A1KMT2AHPGDHTTADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578849-B1 | Process for the preparation of 1,3-dioxane-4,6-dione derivates | BIOGAL GYOGYSZERGYAR (HU) | 1995-05-17 | — | — | EP | disclosed |
| EP-0578849-A1 | Process for the preparation of 1,3-dioxane-4,6-dione derivates | BIOGAL GYOGYSZERGYAR (HU) | 1994-01-19 | — | — | EP | disclosed |