SCHEMBL9196151

SCHEMBL9196151

COc1ccc(CCCCN(C(=O)C(c2ccccc2)c2ccccc2)[C@@H](CCCNC(=N)N)C(=O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 2/20 0.43
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
PLAAT3 P53816 1/20 0.40
PLAAT5 Q96KN8 1/20 0.40
PLAAT2 Q9NWW9 1/20 0.40
PLAAT4 Q9UL19 1/20 0.40
CASR P41180 1/20 0.40
ITGB3 P05106 1/20 0.40
ITGA2B P08514 1/20 0.40
SLC6A5 Q9Y345 2/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9196147 1.00 ALDH1A1 (0.43) ALDH1A1KMT2ACNR1CNR2PLAAT3
SCHEMBL9194821 0.95 ALDH1A1 (0.42) ALDH1A1KMT2ACNR1CNR2PLAAT3
SCHEMBL9194825 0.95 ALDH1A1 (0.42) ALDH1A1KMT2ACNR1CNR2PLAAT3
SCHEMBL8058871 0.89 ALDH1A1 (0.42) ALDH1A1KMT2ACNR1CNR2PLAAT3
SCHEMBL9195083 0.89 CNR1 (0.43) ALDH1A1KMT2ACNR1CNR2CASR
SCHEMBL9194746 0.89 CNR1 (0.43) ALDH1A1KMT2ACNR1CNR2CASR
SCHEMBL8069677 0.87 CNR1 (0.42) ALDH1A1KMT2ACNR1CNR2CASR
SCHEMBL9196992 0.86 CNR1 (0.42) ALDH1A1KMT2ACNR1CNR2CASR
SCHEMBL8069354 0.86 CASR (0.45) ALDH1A1KMT2ACNR1CNR2CASR
SCHEMBL9199630 0.85 MTNR1A (0.44) KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0680469-A1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME Dr. Karl Thomae GmbH (DE) 1995-11-08 EP disclosed
WO-1994017035-A1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME DR. KARL THOMAE GMBH (DE) 1994-08-04 WO disclosed