SCHEMBL9196462

SCHEMBL9196462

Cc1ccccc1NC(=O)/C=C/C=C/C1(F)CC1c1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 5/20 0.40
MMP2 P08253 5/20 0.40
MMP9 P14780 5/20 0.40
EGFR P00533 2/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
P2RX7 Q99572 1/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
TUBB4A P04350 2/20 0.34
TUBB P07437 2/20 0.34
TUBA3C P0DPH7 2/20 0.34
TUBA1B P68363 2/20 0.34
TUBA4A P68366 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9196803 0.91 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9193927 0.88 LMNA (0.36) EGFRKDM4ESMN1; SMN2MAPTALDH1A1
SCHEMBL9190959 0.84 MMP1 (0.42) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9191694 0.83 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9191690 0.83 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9455405 0.83 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9188945 0.83 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9190956 0.83 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9194287 0.82 KDM4E (0.47) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9188997 0.80 LMNA (0.36) EGFRKDM4EMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524041-B1 Pesticides ROUSSEL UCLAF (FR) 1995-09-20 EP claimed