SCHEMBL9196803

SCHEMBL9196803

Cc1ccccc1NC(=O)/C=C/C=C/C1(F)CC1c1ccc(Cl)c(Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 7/20 0.40
MMP2 P08253 7/20 0.40
MMP9 P14780 7/20 0.40
EGFR P00533 2/20 0.40
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CCR3 P51677 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
TAS1R2 Q8TE23 1/20 0.34
P2RX7 Q99572 1/20 0.34
LMNA P02545 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
RORC P51449 1/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34
TUBB4A P04350 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9196462 0.91 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9190705 0.89 ALDH1A1 (0.35) KDM4ELMNAALDH1A1MAPTGAA
SCHEMBL9188997 0.89 LMNA (0.36) EGFRKDM4ELMNAALDH1A1MAPT
SCHEMBL9455335 0.87 MMP1 (0.36) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9191694 0.86 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9188945 0.86 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9455405 0.86 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9190956 0.86 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9191690 0.86 MMP1 (0.40) MMP1MMP2MMP9EGFRKDM4E
SCHEMBL9190959 0.85 MMP1 (0.42) MMP1MMP2MMP9EGFRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524041-B1 Pesticides ROUSSEL UCLAF (FR) 1995-09-20 EP claimed