Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602112 | 0.88 | CYP3A4 (0.51) | LMNAALDH1A1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL27650409 | 0.85 | KDM4E (0.48) | ADRA2ALMNAHIF1AKDM4EADRA2C | |
| SCHEMBL6055405 | 0.84 | CYP3A4 (0.50) | ALDH1A1CYP2D6CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL25066278 | 0.84 | CYP2D6 (0.42) | LMNAALDH1A1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL13795689 | 0.84 | CYP2D6 (0.42) | LMNAALDH1A1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL8285923 | 0.84 | CYP2D6 (0.42) | LMNAALDH1A1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL9205996 | 0.83 | CYP3A4 (0.43) | ADRA2ALMNAHIF1AKDM4EADRA2C | |
| Hydrochloric Acid SCHEMBL4936305 | 0.82 | ALDH1A1 (0.44) | LMNAALDH1A1CYP2D6CYP3A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL14120793 | 0.82 | ALDH1A1 (0.44) | LMNAALDH1A1CYP2D6CYP3A4SLC6A2 | |
| SCHEMBL11079734 | 0.80 | GABRA1 (0.37) | LMNAALDH1A1CYP2D6CYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485069-B1 | Process for producing optically active amines | SUMITOMO CHEMICAL CO (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-5200561-A | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5145998-A | Reduction of oxime or silyloxime | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0237305-B1 | A METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0485069-A1 | Process for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0237305-A2 | A method for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-16 | — | — | EP | disclosed |