Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17018490 | 0.86 | PNMT (0.39) | KDM4ELMNAADRA2AHIF1AADRA2C | |
| SCHEMBL17018493 | 0.86 | PNMT (0.39) | KDM4ELMNAADRA2AHIF1AADRA2C | |
| SCHEMBL17018492 | 0.86 | PNMT (0.39) | KDM4ELMNAADRA2AHIF1AADRA2C | |
| SCHEMBL17018489 | 0.86 | PNMT (0.39) | KDM4ELMNAADRA2AHIF1AADRA2C | |
| SCHEMBL9197147 | 0.85 | ADRA2A (0.48) | KDM4ELMNAADRA2AHIF1AADRA2C | |
| SCHEMBL27651476 | 0.84 | PNMT (0.43) | LMNAALDH1A1CYP2D6PNMTDPP4 | |
| SCHEMBL2778070 | 0.82 | PNMT (0.41) | KDM4ELMNAADRA2AHIF1AADRA2C | |
| SCHEMBL27995634 | 0.82 | PNMT (0.41) | KDM4ELMNAADRA2AHIF1AADRA2C | |
| SCHEMBL394900 | 0.77 | GABRA1 (0.44) | LMNAHIF1ABLMHTR2BPNMT | |
| SCHEMBL28208053 | 0.77 | PNMT (0.44) | PNMTDPP4TSHROPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1867571-A | In situ preparation of chiral derivatives of oxaborolidine-borane complexes, useful in asymmetric reduction reactions of etheroximes or ketones to chiral alcohols or amines | PPG SIPSY (FR) | 2006-11-22 | — | — | CN | disclosed |