Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | CEL | P19835 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196131 | 1.00 | MEN1 (0.34) | MEN1KMT2AMAPK1ELANECYSLTR2 | |
| SCHEMBL9198902 | 0.95 | PPARG (0.32) | MAPK1ELANEPPARGPPARAMAPT | |
| SCHEMBL9198707 | 0.90 | CEL (0.41) | MEN1KMT2AMAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL9197301 | 0.89 | ELANE (0.34) | MEN1KMT2AELANECYSLTR2CYSLTR1 | |
| SCHEMBL6173632 | 0.87 | CEL (0.40) | MEN1KMT2AMAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL6175129 | 0.86 | ELANE (0.33) | MEN1KMT2AELANECELMAPT | |
| SCHEMBL9199733 | 0.85 | ELANE (0.33) | ELANEMAPT | |
| SCHEMBL9193978 | 0.85 | MAPK1 (0.34) | MEN1KMT2AMAPK1FEN1 | |
| SCHEMBL9197893 | 0.85 | HPGD (0.40) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9196698 | 0.83 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |