Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774438 | 0.80 | SLC6A3 (0.41) | SLC6A2SLC6A3SLC6A4ALDH1A1TSHR | |
| SCHEMBL6207732 | 0.79 | PRCP (0.41) | SLC6A2SLC6A3SLC6A4TLR2PRCP | |
| SCHEMBL8569265 | 0.79 | PRCP (0.41) | SLC6A2SLC6A3SLC6A4TLR2PRCP | |
| SCHEMBL3982507 | 0.79 | PRCP (0.41) | SLC6A2SLC6A3SLC6A4TLR2PRCP | |
| SCHEMBL7804926 | 0.78 | SLC6A3 (0.34) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL856505 | 0.78 | SLC6A3 (0.39) | SLC6A2SLC6A3SLC6A4TLR2PRCP | |
| SCHEMBL30166189 | 0.77 | SLC6A3 (0.40) | SLC6A2SLC6A3SLC6A4TLR2PRCP | |
| SCHEMBL6047342 | 0.75 | SLC6A3 (0.39) | SLC6A2SLC6A3SLC6A4ALDH1A1TSHR | |
| SCHEMBL5742756 | 0.73 | ATM (0.47) | TLR2ATMPRCPDPP7ALDH1A1 | |
| SCHEMBL28063029 | 0.73 | ATM (0.47) | TLR2ATMPRCPDPP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651749-A1 | IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1995-05-10 | — | — | EP | disclosed |