SCHEMBL9197897

SCHEMBL9197897

O=c1[nH]cc(CCCC(O)CO)c(=O)[nH]1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
MAPT P10636 1/20 0.38
HCAR3 P49019 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6038033 0.82 GAA (0.40) GAA
SCHEMBL23610067 0.81 GAA (0.47) GAAMAPT
SCHEMBL7607239 0.80 GAA (0.46) GAAMAPT
SCHEMBL6038035 0.79 GAA (0.41) GAAMAPT
SCHEMBL7070324 0.77 GAA (0.50) GAAMAPT
SCHEMBL4353311 0.76 DPYD (0.50) GAAMAPT
SCHEMBL7599681 0.74 ALDH1A1 (0.45) GAAMAPT
SCHEMBL356483 0.74 TYMP (0.49) HCAR3HCAR2
SCHEMBL7598825 0.73 F13A1 (0.44) GAA
SCHEMBL44459 0.73 GAA (0.52) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0133473-B1 In vivo labelling of polynucleotide sequences ENZO BIOCHEM INC (US) 1994-03-23 EP claimed
US-5476931-A Reacting with a base in a mixed solvent containing alcohol RIKAGAKU KENKYUSHO (JP) 1995-12-19 US disclosed
EP-0311694-B1 NUCLEOSIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION RIKAGAKU KENKYUSHO (JP) 1995-12-13 EP disclosed
EP-0133473-B1 In vivo labelling of polynucleotide sequences ENZO BIOCHEM INC (US) 1994-03-23 EP disclosed
US-5144018-A Antiviral Agents RIKAGAKU KENKYUSHO (JP) 1992-09-01 US disclosed
US-4987065-A GENETIC ENGINEERING ENZO BIOCHEM, INC. (US) 1991-01-22 US disclosed
EP-0147689-B1 A METHOD OF INDUCING ANTITUMOR IMMUNOCYTES, AND A PROCESS FOR PRODUCING ANTITUMOR IMMUNOCYTES AND ANTITUMOR IMMUNOCYTES PRODUCED BY THE PROCESS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-09-19 EP disclosed
US-4839290-A ANTITUMOR IMMUNOCYTES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1989-06-13 US disclosed
EP-0311694-A1 NUCLEOSIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION RIKAGAKU KENKYUSHO (JP) 1989-04-19 EP disclosed
EP-0147689-A2 A method of inducing antitumor immunocytes, and a process for producing antitumor immunocytes and antitumor immunocytes produced by the process Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-07-10 EP disclosed
EP-0133473-A2 In vivo labelling of polynucleotide sequences ENZO BIOCHEM, INC. (US) 1985-02-27 EP disclosed