SCHEMBL356483

SCHEMBL356483

CCCCc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TYMP P19971 3/20 0.49
FFAR3 O14843 1/20 0.46
HCAR3 P49019 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
ATAD2 Q6PL18 1/20 0.45
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL357910 0.94 TYMP (0.50) TYMPHCAR2ATAD2
SCHEMBL6573665 0.93 TYMP (0.51) TYMPHCAR2ATAD2
SCHEMBL156784 0.88 ATAD2 (0.48) TYMPHCAR2ATAD2
SCHEMBL4353311 0.83 DPYD (0.50) ATAD2
SCHEMBL10983716 0.81 KMT2A (0.53) TYMPFFAR3HCAR3HCAR2KDM4E
SCHEMBL161148 0.81 ATAD2 (0.54) ATAD2
SCHEMBL23610067 0.81 GAA (0.47) ATAD2
SCHEMBL7599681 0.81 ALDH1A1 (0.45) ATAD2
SCHEMBL29767278 0.80 HCAR2 (0.50) HCAR2ATAD2
SCHEMBL7603360 0.79 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024026372-A2 HYDROGEN BONDING BOTTLEBRUSH POLYMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-02-01 WO claimed
US-20150211004-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-07-30 US claimed
EP-2838541-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES Agency For Science, Technology And Research (SG) 2015-02-25 EP claimed
WO-2013158046-A1 RNAI-BASED THERAPIES FOR CARDIOMYOPATHIES, MUSCULAR DYSTROPHIES AND LAMINOPATHIES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-10-24 WO claimed
EP-0637965-B1 ENHANCED TRIPLE-HELIX AND DOUBLE-HELIX FORMATION WITH OLIGOMERS CONTAINING MODIFIED PYRIMIDINES ISIS PHARMACEUTICALS INC (US) 2002-10-16 EP claimed
US-12606814-B2 Oligonucleotide probes and uses thereof CARIS SCIENCE, INC. (US) 2026-04-21 US disclosed
US-20260078383-A1 RNA NANOSTRUCTURES AND METHODS OF MAKING AND USING RNA NANOSTRUCTURES UNIV ARIZONA STATE (US) 2026-03-19 US disclosed
US-12577627-B2 Selective detection of different dengue virus RNA serotypes using tandem toehold-mediated displacement reactions ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONE STATE UNIVERSITY (US) 2026-03-17 US disclosed
US-20260041702-A1 AGENTS THAT INHIBIT CCN LIGAND-INDUCED SIGNALLING FOR TREATING DISEASE TRIBUNE THERAPEUTICS AB (SE) 2026-02-12 US disclosed
EP-4683716-A1 DNA NANODEVICES FOR SPECIFIC AND EFFICIENT DELIVERY OF FUNCTIONAL PAYLOADS TO THE CYTOPLASM AND METHODS OF THEIR USE Arizona Board of Regents on behalf of Arizona State University (US) 2026-01-28 EP disclosed
EP-4680212-A1 ADAR1 INHIBITORS FOR TREATING CANCER Institute of Cancer Research Royal Cancer Hospital (GB) 2026-01-21 EP disclosed
US-20260014278-A1 HYBRID PEPTIDE DENDRIMER SYSTEMS AND EXTRAHEPATIC DELIVERY NUNTIUS THERAPEUTICS LTD (GB) 2026-01-15 US disclosed
EP-0515464-B1 PROCESS FOR PREPARING URACIL DERIVATIVES ERBA CARLO SPA (IT) 1994-10-19 EP disclosed
US-5286861-A Process for preparing uracil derivatives FARMITALIA CARLO ERBA S.R.L. (IT) 1994-02-15 US disclosed
EP-0572529-A1 APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING GILEAD SCIENCES, INC. (US) 1993-12-08 EP disclosed
WO-1992014842-A1 APTAMERS SPECIFIC FOR THROMBIN AND METHODS OF USE GILEAD SCIENCES, INC. (US) 1992-09-03 WO disclosed
WO-1992014843-A1 APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING GILEAD SCIENCES, INC. (US) 1992-09-03 WO disclosed
WO-1991013064-A1 PROCESS FOR PREPARING URACIL DERIVATIVES FARMITALIA CARLO ERBA S.R.L. (IT) 1991-09-05 WO disclosed
US-4182859-A Process for the preparation of 2'-deoxyribofuranosyl nucleosides ROBUGEN GMBH PHARMACEUTISCHE FABRIK (DE) 1980-01-08 US disclosed
US-3935184-A Synthetic polyoxin type nucleosides SYNTEX (U.S.A.) INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577627-B2 Selective detection of different dengue virus RNA serotypes using tandem toehold-mediated displacement reactions DDX41, DDX5, DDX6 TYMP 2886/4885FFAR3 3231/4885HCAR3 3638/4885
US-12606814-B2 Oligonucleotide probes and uses thereof CD63, FLT4, NCL TYMP 814/4885FFAR3 1842/4885HCAR3 4329/4885
US-20260041702-A1 AGENTS THAT INHIBIT CCN LIGAND-INDUCED SIGNALLING FOR TREATING DISEASE PKD2, CCNK, PKD1 TYMP 1238/4885FFAR3 2644/4885HCAR3 3924/4885
US-20260078383-A1 RNA NANOSTRUCTURES AND METHODS OF MAKING AND USING RNA NANOSTRUCTURES PDCD1, TIA1, NSUN2 TYMP 2547/4885FFAR3 3610/4885HCAR3 3994/4885
US-20260014278-A1 HYBRID PEPTIDE DENDRIMER SYSTEMS AND EXTRAHEPATIC DELIVERY CD47, CD2BP2, CD40LG TYMP 1157/4885FFAR3 1039/4885HCAR3 2616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.