Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955897 | 0.82 | KCNH2 (0.47) | KCNH2GRIA4TSHR | |
| SCHEMBL9004469 | 0.77 | GFER (0.36) | ESR1ESR2THRBMEN1KMT2A | |
| SCHEMBL1149698 | 0.76 | TAAR1 (0.50) | THRBTHRATSHR | |
| SCHEMBL8077541 | 0.76 | THRB (0.52) | THRBMEN1KMT2ATHRATSHR | |
| SCHEMBL6285109 | 0.75 | GFER (0.41) | ESR1ESR2THRBMEN1KMT2A | |
| SCHEMBL8803722 | 0.75 | TAAR1 (0.55) | — | |
| SCHEMBL18237103 | 0.73 | ESR1 (0.55) | ESR1ESR2MEN1KMT2ATSHR | |
| SCHEMBL4636535 | 0.72 | THRB (0.55) | ESR1THRBMEN1KMT2ATHRA | |
| SCHEMBL8956085 | 0.72 | KCNH2 (0.53) | KCNH2GRIA4TSHR | |
| SCHEMBL10339190 | 0.71 | ESR1 (0.46) | ESR1ESR2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663904-A1 | FUNGICIDAL SUBSTITUTED AZOLE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1995-07-26 | — | — | EP | disclosed |