Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3092054 | 0.75 | GLA (0.67) | ALDH1A1MAPTHSD17B10KDM4CSIRT2 | |
| SCHEMBL5428977 | 0.73 | SIRT1 (0.43) | ALDH1A1SIRT2SIRT1LMNA | |
| SCHEMBL9196946 | 0.72 | GLA (0.51) | ALDH1A1MAPTHSD17B10KDM4CSIRT2 | |
| SCHEMBL9200533 | 0.70 | NPSR1 (0.49) | ALDH1A1MAPTHSD17B10SIRT2SMN1; SMN2 | |
| SCHEMBL9197955 | 0.69 | SIRT1 (0.74) | SIRT2SIRT1 | |
| SCHEMBL30019852 | 0.69 | MAPT (0.60) | ALDH1A1MAPTHSD17B10KDM4CSIRT2 | |
| SCHEMBL11280668 | 0.68 | SMN1; SMN2 (0.44) | ALDH1A1MAPTHSD17B10KDM4CSIRT2 | |
| SCHEMBL30018700 | 0.67 | SIRT2 (0.75) | ALDH1A1MAPTHSD17B10KDM4CSIRT2 | |
| SCHEMBL9194449 | 0.66 | HSD17B10 (0.50) | ALDH1A1MAPTHSD17B10SIRT1SMN1; SMN2 | |
| SCHEMBL8188358 | 0.66 | ALDH1A1 (0.47) | ALDH1A1MAPTSIRT2SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578849-B1 | Process for the preparation of 1,3-dioxane-4,6-dione derivates | BIOGAL GYOGYSZERGYAR (HU) | 1995-05-17 | — | — | EP | disclosed |
| EP-0578849-A1 | Process for the preparation of 1,3-dioxane-4,6-dione derivates | BIOGAL GYOGYSZERGYAR (HU) | 1994-01-19 | — | — | EP | disclosed |