Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205495 | 0.88 | SMN1; SMN2 (0.36) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8986727 | 0.82 | SMN1; SMN2 (0.39) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9592232 | 0.79 | ALDH1A1 (0.40) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9205492 | 0.76 | TRPV1 (0.40) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9198962 | 0.75 | HSD17B10 (0.30) | — | |
| SCHEMBL8986729 | 0.71 | SMN1; SMN2 (0.40) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8438552 | 0.70 | SMN1; SMN2 (0.42) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9594743 | 0.64 | ALDH1A1 (0.41) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7456808 | 0.64 | SMN1; SMN2 (0.46) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8438550 | 0.62 | NPC1 (0.45) | LMNAHTTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418667-B1 | Carboxylic acid amides | BASF AG (DE) | 1995-08-16 | — | — | EP | disclosed |
| EP-0418667-A2 | Carboxylic acid amides | BASF Aktiengesellschaft (DE) | 1991-03-27 | — | — | EP | disclosed |