Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198518 | 0.88 | LMNA (0.36) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL8986729 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL9205492 | 0.80 | TRPV1 (0.40) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL8438552 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL9592232 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL8986727 | 0.71 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL7456808 | 0.65 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL8986726 | 0.64 | TRPV1 (0.44) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL8438550 | 0.63 | NPC1 (0.45) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL9594743 | 0.62 | ALDH1A1 (0.41) | SMN1; SMN2LMNANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418667-B1 | Carboxylic acid amides | BASF AG (DE) | 1995-08-16 | — | — | EP | disclosed |