Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | DRD5 | P21918 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17197050 | 0.86 | HRH3 (0.60) | HRH3HTR2AHTR2BLMNAUSP2 | |
| SCHEMBL7132136 | 0.81 | LTA4H (0.70) | HRH3LTA4H | |
| SCHEMBL1730306 | 0.81 | LTA4H (0.77) | HRH3LTA4HHTR1ADRD2HTR2A | |
| SCHEMBL19560190 | 0.80 | LTA4H (0.67) | HRH3LTA4HHTR2AHTR2BLMNA | |
| SCHEMBL13698800 | 0.80 | USP2 (0.73) | HRH3LTA4HHTR1ADRD2HTR2A | |
| SCHEMBL5366151 | 0.80 | KCNH2 (0.48) | HRH3HTR1ADRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL1730768 | 0.79 | USP2 (0.71) | HRH3LTA4HHTR1ADRD2HTR2A | |
| SCHEMBL13698801 | 0.77 | LTA4H (0.87) | HRH3LTA4HMEN1LMNAHTT | |
| SCHEMBL19389962 | 0.77 | LTA4H (0.57) | HRH3LTA4HHTR1ADRD2HTR2A | |
| SCHEMBL1728918 | 0.76 | USP2 (0.78) | HRH3LTA4HHTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520882-B1 | 2-Aminopyrimidin-4-carboxamide derivatives, their preparation and their application in therapy | SYNTHELABO (FR) | 1995-07-12 | — | — | EP | disclosed |
| US-5246939-A | Antiadrenergic systems for lower urinary apparatus | SYNTHELABO (FR) | 1993-09-21 | — | — | US | disclosed |
| EP-0520882-A1 | 2-Aminopyrimidin-4-carboxamide derivatives, their preparation and their application in therapy | SYNTHELABO (FR) | 1992-12-30 | — | — | EP | disclosed |