Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12321327 | 0.87 | GRIN2D (0.53) | HRH3DRD2SLC6A4PSMB1PSMB5 | |
| SCHEMBL12278101 | 0.84 | KMT2A (0.56) | LTA4HHRH3MEN1HTTKMT2A | |
| SCHEMBL23291189 | 0.82 | HRH3 (0.49) | LTA4HHRH3DRD2PSMB1PSMB5 | |
| SCHEMBL1730306 | 0.80 | LTA4H (0.77) | LTA4HHRH3MEN1LMNAHTT | |
| SCHEMBL25381352 | 0.80 | TBXAS1 (0.48) | LTA4HHRH3HTTDRD2HRH1 | |
| SCHEMBL13290237 | 0.80 | MCHR1 (0.75) | HRH3MCHR1 | |
| SCHEMBL22137693 | 0.77 | LTA4H (0.63) | LTA4HHRH3HTR1AHTR7MCHR1 | |
| SCHEMBL82404 | 0.77 | HRH3 (0.59) | LTA4HHRH3ALDH1A1DRD2PSMB1 | |
| SCHEMBL9199004 | 0.77 | HRH3 (0.60) | LTA4HHRH3MEN1LMNAHTT | |
| SCHEMBL17198029 | 0.76 | LTA4H (0.59) | LTA4HHRH3DRD2TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083562-B1 | PHENOXYETHYL CYCLIC AMINE DERIVATIVES AND THEIR ACTIVITY AS EP4 RECEPTOR MODULATORS | LILLY CO ELI (US) | 2017-09-27 | — | — | EP | disclosed |