Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SELE | P16581 | 6/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801211 | 0.68 | ALDH1A1 (0.45) | ALDH1A1LMNASELEVCAM1ICAM1 | |
| SCHEMBL28797393 | 0.67 | — | — | |
| SCHEMBL14719008 | 0.66 | — | — | |
| SCHEMBL4803560 | 0.66 | SELE (0.38) | ALDH1A1LMNASELEVCAM1ICAM1 | |
| SCHEMBL1993811 | 0.65 | KAT2B (0.31) | — | |
| SCHEMBL4467490 | 0.65 | ALDH1A1 (0.41) | ALDH1A1LMNASELEVCAM1ICAM1 | |
| SCHEMBL6771634 | 0.65 | CYP1A2 (0.32) | CYP1A2TSHR | |
| SCHEMBL15879962 | 0.65 | CYP2A6 (0.46) | ALDH1A1LMNATSHRHPGDKMT2A | |
| SCHEMBL2870722 | 0.64 | NPC1 (0.40) | SELEVCAM1KMT2ATDP1NPC1 | |
| SCHEMBL1821367 | 0.63 | CYP1A2 (0.31) | CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304155-B1 | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions | ZENECA PHARMA SA (FR) | 1995-11-15 | — | — | EP | disclosed |
| US-5013730-A | Antibiotics | ICI-PHARMA (FR) | 1991-05-07 | — | — | US | disclosed |
| EP-0304155-A2 | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions | ZENECA Pharma S.A. (FR) | 1989-02-22 | — | — | EP | disclosed |